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Improve Your Process Economy and Control
For Peptide and Oligonucleotide Manufacturing
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PeptiSystems Products
Research and Laboratory | Process Development | Large-scale production | Clinical trials
PeptiSystems offers a new generation of instruments for solid-phase synthesis production of peptide and oligonucleotide therapeutics. Our instruments are used within the biopharmaceutical and biotech industry for process development and large-scale GMP and non-GMP manufacturing based on flowthrough column technology.
Chemistry first - our instruments are designed from a chemistry perspective to give maximum flexibility and control without compromise.
Our Technology
Our patent-pending technology based on continuous flow is changing the way peptide and oligonucleotide therapeutics are manufactured.
Faster
Fully automated instruments with as little as 1-3 hour cycle time resulting in up to 10x faster manufacturing compared to using batch reactor technology. Flexible process development using pilot-scale instruments makes it easy to optimize the synthesis method and smoothly transfer for large-scale manufacturing.
Easy Scale-up
Unique linear scale-up technology uses the same synthesis parameters from process development in large-scale manufacturing. This means that it takes the same amount of time to synthesize in small-scale as in large-scale. Supports up to 5 mol.
Improved Control
Specifically designed for peptide and oligonucleotide synthesis. Real-time monitoring and graphical presentation of key parameters provides continuous detailed insight into synthesis progress and sends alarms/messages if needed.
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PeptiPilot and PeptiPilot Plus
R&D | Process Development | Pre-clinical and clinical trials
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Scale: 0.1-12 mmol (PeptiPilot) and 4-40 mmol (PeptiPilot Plus).
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Supports using industry standard resins, reagents and solvents.
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50-90% reduction of synthesis time from weeks to 1-3 days.
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Increase yield and purity by up to 15%.
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Reduce solvent consumption by up to 50%.
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Automates the synthesis, reducing cycle time to 1-3h.
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Continuous real-time monitoring tracks the progress in each synthesis step.
PeptiPro
Large-scale synthesis | GMP Commercial Production | Clinical Trials
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Scale: customizable from 10 mmol up to 5 mol per batch.
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Fully automated for large-scale/commercial manufacturing.
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Smooth transfer of synthesis method from PeptiPilot and PeptiPilot Plus.
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Continuous real-time monitoring tracks the progress in each synthesis step.
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Consistently high reproducibility and same short synthesis time as with PeptiPilot and PeptiPilot Plus.
OligoNavigator and OligoNavigator Plus
R&D | Process Development | Clinical trials | Pre-clinical material
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Scale: 0.1-12 mmol (OligoNavigator) and 1-30 mmol (Plus).
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Up to 12 amidite building block inlets.
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Flexible and easy-to-use software matrix for setting parameters for synthesis.
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In-line heater for temperature control and heating up to 50°C.
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Diode array and conductivity monitors.
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Synthesis method is easily transferred to OligoNavigator Pro.
OligoNavigator Pro
Large-scale synthesis | GMP Commercial Production | Clinical trials
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Scale: customizable from 10 mmol up to 5 mol per batch.
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Fully automated for large-scale/commercial manufacturing.
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Smooth transfer of synthesis method from OligoNavigator and Plus instruments.
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Consistently high reproducibility and same short synthesis time as with OligoNavigator and OligoNavigator Plus.
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Extremely accurate pump system (+-0.05%) that adds the correct amount of liquid to the system to save on costs and improve synthesis control.
Uppsala Business Park, Sweden